While driving aimlessly after a quarrel with his girlfriend, a writer accidentally runs over and kills a child. The accident and its aftermath deeply traumatizes him. Over the next 12 years, he struggles to make sense of what happened and continue on with life, but when he looks in the mirror, he sees a murderer.

Wim Wenders talks with Japanese fashion designer Yohji Yamamoto about the creative process and ponders the relationship between cities...

Seth is an angel who accompanies the spirits of the recently dead to the ever after. Seth has never been human and so has has never experienced touch or taste. When in the hospital however he comes across Dr. Maggie Rice, a brilliant young heart surgeon who is devoted to her profession and her patients. Seth has the power to let himself be seen but Maggie finds him far too mysterious. Seth also meets a patient, Nathaniel Messinger, who has news for him - he too was once an angel like Seth but chose to fall to Earth and become human. Seth makes a decision on his future, which does not turn out as he had expected.

After the wild life-style of a famous young German photographer almost gets him killed, he goes to Palermo, Sicily to take a break. Can the beautiful city and a beautiful local woman help him calm himself down?